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Mizzou researchers bring hope to people with rare neurological condition

Jun 14, 2012

Animal modeling is a big part of the One Health/One Medicine initiative, and this story features a new animal model.

From Mizzou Weekly

MU scientists have created a genetically modified mouse that mimics key features of Charcot-Marie-Tooth disease, an inherited neuromuscular disease infecting some 150,000 people in the United States.

Charcot-Marie-Tooth, or CMT, is a group of progressive disorders that harms the peripheral nervous system, the part that connects the brain and spinal cord to things like muscles.

The disease largely affects the distal nerves, which are those running to the feet and hands, and can progress to include the legs and arms. More