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Featured Profile: D. Cornelison

D. Cornelison

University of Missouri researcher D Cornelison is uncovering how skeletal muscles develop and regenerate.

For more than 20 years, Cornelison has studied the role of muscle stem cells, called satellite cells, in tissue regeneration. When a muscle is damaged, these cells multiply, migrate to the site of injury and rapidly start repairing muscle fibers. Which signals direct these activities, and where the signals come from, has been the focus of Cornelison’s research at MU.

Cornelison is a pioneer in satellite cell movement analysis. Using time lapse movies taken through a microscope of satellite cells on muscle fibers, her laboratory was the first to describe where, when and how fast these cells move. More recently, Cornelison’s team identified a family of signals that dictate which neurons are allowed to supply nerve signals to different kinds of muscle fibers (slow or fast). They are now studying what roles these signals play in communication between all of the different cell types found in muscle (satellite cells, muscle fibers, nerves, blood vessels, etc.) so that they can work together to regenerate the tissue.

Cornelison is the recipient of a Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the United States government on science and engineering professionals in the early stages of their independent research careers.

Dr. D Cornelison is an associate professor of biological sciences in the College of Arts and Science with an adjunct appointment in the School of Medicine. She is also an investigator at MU’s Bond Life Sciences Center.

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Related Initiative(s):
One Health/One Medicine