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Featured Profile: Salman Hyder

Salman Hyder

University of Missouri researcher Dr. Salman Hyder is a leading expert on tumor development.

Hyder works to develop new treatments for diseases of the endocrine system including breast, uterine and prostate cancer. He investigates molecular substances that can be affected by hormones or steroids, which can be used to halt the development of new blood vessels involved in tumor growth. Hyder has found that luteolin, a natural compound found in certain herbs and vegetables, could reduce breast cancer risk for women who have taken hormone replacement therapy. He also proved that a compound called RO 48-8071, initially developed as a cholesterol-fighting molecule, not only halts the progression of cancer but also can kill cancerous cells.

Additionally, Hyder has discovered new insights about progesterone, a hormone common in birth control and treatments for menopause. His research shows that progesterone actively promotes the progression of human breast cancer cells in an animal model. Previously such observations had been limited to animal cells. Hyder’s work adds to scientists’ understanding of the processes behind tumor growth. “If we could control these processes, we could potentially control tumor growth and metastasis,” he says, “and thereby alleviate much suffering and save many lives.”

Dr. Salman Hyder is the Zalk Missouri Professor of Tumor Angiogenesis in the College of Veterinary Medicine and an investigator at Dalton Cardiovascular Research Center.

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Related Initiative(s):
One Health/One Medicine